The Bottom Line. Qsymia is a prescription-only weight loss medication that, when used in conjunction with diet and exercise, has a proven track record in overweight and obese individuals. The most common adverse effects are abnormal skin sensations, dizziness, altered taste, insomnia, constipation, and dry mouth, more severe issues can occur.Mar 29, 2022 · Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ... Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ...Sep 30, 2022 · Along with its needed effects, liraglutide (the active ingredient contained in Saxenda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking liraglutide: More common. Bladder pain Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.Jun 28, 2023 · After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active. You can do this by taking certain adrenal support supplements, eliminating stressors in your life, eating a healthy diet, taking advantage of low-intensity exercises at night, carbohydrate cycling, and using meditation. Optimizing your adrenal glands for 1-2 months prior to using phentermine may be ideal for many thyroid patients.The SELECT trial is the long-term cardiovascular outcomes trial for Wegovy that aims to assess its effects on heart disease and stroke in patients with overweight and obesity; it is currently ongoing and expected to be completed in September 2023. Anti-obesity medication management: An evolving landscapeLong-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.Jan 25, 2021 · These are the most common Topamax side effects, according to the manufacturer: Loss of appetite, changes in taste, weight loss, stomach pain, and even anorexia. GI side effects (nausea, diarrhea, indigestion) Tiredness. Paresthesia (tingling or prickling sensations) Speech problems. Cognitive dysfunction (trouble with memory and thinking) Upper ... Jun 28, 2023 · After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active. Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body.May 15, 2023 · On the positive side, lower doses of semaglutide, the active ingredient in Wegovy, have been used to treat diabetes for several years now, though UpToDate, a site that aggregates research about treatments to support decision-making by physicians, notes that there have been very few trials lasting more than four years, so the long-term safety of ... This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.Feb 3, 2023 · Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ... Along with its needed effects, liraglutide (the active ingredient contained in Saxenda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking liraglutide: More common. Bladder painQsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ... What Are Side Effects of Qsymia? Side effects of Qsymia can include: mood changes such as depression, trouble sleeping (insomnia), confusion, dizziness, anxiety, tiredness, irritability, constipation, numbness or tingly feeling, altered sense of taste, dry mouth, unpleasant taste in your mouth, headache, upper respiratory tract infection,Nov 2, 2022 · Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use. Feb 1, 2023 · Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription. Sep 30, 2022 · Along with its needed effects, liraglutide (the active ingredient contained in Saxenda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking liraglutide: More common. Bladder pain Qsymia has an average rating of 7.7 out of 10 from a total of 564 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 15% reported a negative experience. Condition.Phentermine acts much like a stimulant and has many of the same side effects: increased heart palpitations. increased blood pressure. dizziness. Phentermine is known for being one part of Fen-Phen ...Phentermine Results after 3 Months. First of all, let us clarify if you take Phentermine HCL without any special diet or exercise plan, it is possible to lose around 8 pounds within the 3 months ...Studies show that on average, people taking Topamax lose around 11 lbs. Higher doses and longer duration of use generally result in more weight loss. The most common side effects associated with Topamax for weight loss are abnormal skin sensations (like burning, tingling, numbness), altered sense of taste, and slowed thinking and movements.COMMON SIDE EFFECTS OF QSYMIA IN CHILDREN 12 YEARS OLD AND OLDER INCLUDE: Depression, dizziness, joint pain, fever, flu, and ankle sprain. POSSIBLE SIDE EFFECTS OF QSYMIA INCLUDE: Mood changes and trouble sleeping. Qsymia may cause depression or mood problems, and trouble sleeping. Tell your healthcare provider if symptoms occur.The highest dose of Qsymia contains only 15mg of Phentermine, but the average dose of Phentermine (for weight loss when used by itself) is 37.5mg. While it may be nice to have a combination medication, it may actually be better to prescribe both medications individually so you have more control over the dosages of each medication.This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment.Apr 30, 2014 · This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment. 1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ...It is used by certain overweight people, such as those who are obese or have weight -related medical problems. Losing weight and keeping it off can lessen the many health risks that come with ...Approved for long-term use? Yes. Qsymia has much lower amounts of phentermine and topiramate than when these drugs are given alone. Side effects: The most common side effects are tingling hands ... The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.Phentermine has the advantage of low cost and many years of clinical experience, but its long-term use is considered off-label, long-term effects on CVD outcomes are unknown, and most use has been a few months or less. 41 There are even fewer data for long-term safety and efficacy of the other noradrenergic agents. Orlistat has a reasonably ...Taking this medication late in the day may cause trouble sleeping ( insomnia ). Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once,... Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance.Qsymia is prescription-only weight loss medication that contains a combination of phentermine HCl and topiramate extended-release. This drug, which received FDA approval in 2012, helps manage obesity longer-term than phentermine alone, but also carries the risk of additional side effects (1, 2).Apr 8, 2013 · PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day. Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ...May 19, 2016 · Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances. trouble sleeping (insomnia) new or worse irritability acting aggressive, being angry, or violent acting on dangerous impulses an extreme increase in activity and talking (mania) other unusual changes in behavior or mood Serious eye problems which include: Qsymia may affect how you think and cause confusion, problems with concentration, attention, memory or speech. Tell your healthcare provider if symptoms occur. Slowing of growth. Qsymia may slow the increase in height in children 12 years and older. Increases of acid in bloodstream (metabolic acidosis). It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.Phentermine acts much like a stimulant and has many of the same side effects: increased heart palpitations. increased blood pressure. dizziness. Phentermine is known for being one part of Fen-Phen ...7. Wegovy (semaglutide) Wegovy is the newest FDA-approved weight-loss medication and works much the same way as Saxenda, by mimicking the action of the hormone GLP-1 to suppress hunger. Wegovy is a once-a-week injectable. Dosage is increased over the course of several weeks-to-months, until a 2.4 mg dose is achieved.Aug 4, 2022 · Other side effects. Some side effects of phentermine / topiramate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ...Mar 22, 2019 · An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest ... It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ... Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months).Mar 29, 2022 · Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ... Sep 30, 2022 · Along with its needed effects, liraglutide (the active ingredient contained in Saxenda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking liraglutide: More common. Bladder pain Aug 4, 2022 · Less common. Chest discomfort. decreased urine. dry mouth. fast, irregular, pounding, or racing heartbeat or pulse. loss of appetite. mood changes. muscle pain or cramps. nausea or vomiting. numbness or tingling in the hands, feet, or lips. seizures. Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ... Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.Uses. This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who ...PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day.Aug 4, 2022 · Less common. Chest discomfort. decreased urine. dry mouth. fast, irregular, pounding, or racing heartbeat or pulse. loss of appetite. mood changes. muscle pain or cramps. nausea or vomiting. numbness or tingling in the hands, feet, or lips. seizures. Mar 29, 2022 · Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ... Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety.Aug 3, 2023 · What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ... Jan 6, 2021 · During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety. Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ...At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months.In fact, this sort of weight loss is referred to as yo-yo dieting (yes, even if it comes secondary to the use of prescription medication) and can cause some serious long-term problems. #2. Using Phentermine Daily Can and Dose Cause Metabolic Damage. Perhaps the single biggest reason to avoid using Phentermine is that it can cause something ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ... Now, semaglutide (under the brand name Wegovy) is FDA approved for weight loss. It can be used by adults with a body mass index (BMI) greater than or equal to 30 mg/kg² alone or 27 mg/kg² with at least one weight-related condition (e.g., high blood pressure, high cholesterol, Type 2 diabetes). Semaglutide is also approved for chronic weight ...Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ...In fact, this sort of weight loss is referred to as yo-yo dieting (yes, even if it comes secondary to the use of prescription medication) and can cause some serious long-term problems. #2. Using Phentermine Daily Can and Dose Cause Metabolic Damage. Perhaps the single biggest reason to avoid using Phentermine is that it can cause something ...After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active.The highest dose of Qsymia contains only 15mg of Phentermine, but the average dose of Phentermine (for weight loss when used by itself) is 37.5mg. While it may be nice to have a combination medication, it may actually be better to prescribe both medications individually so you have more control over the dosages of each medication.Feb 28, 2023 · The Saxenda Savings Card allows you to pay as little as a $25 copay or save up to $200 per Saxenda prescription. The Savings Card program allows for up to 12 benefits annually. There are eligibility requirements, and other restrictions apply. According to GoodRX, out-of-pocket prices range from $1332.59 to $1432.91. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.
These are the most common Topamax side effects, according to the manufacturer: Loss of appetite, changes in taste, weight loss, stomach pain, and even anorexia. GI side effects (nausea, diarrhea, indigestion) Tiredness. Paresthesia (tingling or prickling sensations) Speech problems. Cognitive dysfunction (trouble with memory and thinking) Upper .... 844 377 4136
Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...On the positive side, lower doses of semaglutide, the active ingredient in Wegovy, have been used to treat diabetes for several years now, though UpToDate, a site that aggregates research about treatments to support decision-making by physicians, notes that there have been very few trials lasting more than four years, so the long-term safety of ...This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... Jan 9, 2023 · Now, semaglutide (under the brand name Wegovy) is FDA approved for weight loss. It can be used by adults with a body mass index (BMI) greater than or equal to 30 mg/kg² alone or 27 mg/kg² with at least one weight-related condition (e.g., high blood pressure, high cholesterol, Type 2 diabetes). Semaglutide is also approved for chronic weight ... 4. Avoid alcohol. Avoid drinking alcohol while taking Qsymia as it can increase your risk of serious side effects, such as central nervous system depression, and an increase in your risk of falls. 5. Don’t skip meals. Eating regular meals and snacks will help to prevent low blood sugar levels (hypoglycemia). 6. Jul 18, 2021 · Paresthesia (tingling, numbness) of the extremities (15-38%) Dizziness (11-28%) Dysgeusia (abnormal taste sensation) (6-19%) Insomnia (7-17%) Constipation (6-16%) Dry mouth (5-14%) Headache (5-14%) Nausea (5-13%) Diarrhea (4-11%) Upper respiratory tract infection (4-9%) Phentermine alone is designed for short-term use only, as there are few long-term studies on its safety. One study observed that people experienced no significant side effects when they took ...Uses. This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who ...However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance.Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ...The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Summary.Jan 11, 2023 · In general, Phentermine chemicals do have side effects on long-term treatment. One of the most common side effects is dry mouth. Aside from this, you may also experience nervousness or jitteriness ... PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day.Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ....